Transposition of Tc1 in the nematode Caenorhabditis elegans.

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چکیده

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Transposition of Tc1 in the nematode Caenorhabditis elegans.

We have identified a strain of Caenorhabditis elegans in which the transposable element Tc1 is genetically active. Most spontaneous mutations affecting the unc-54 myosin heavy chain gene of C. elegans variety Bergerac are due to insertions of Tc1 within unc-54. The Bergerac genome contains an unusually high number of Tc1 elements, but this is not responsible for transpositional activity. Anothe...

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BACKGROUND Transposable elements of the Tc1/mariner family are found in many species of the animal kingdom. It has been suggested that the widespread distribution of this transposon family resulted from horizontal transmission among different species. RESULTS To test the ability of Tc1/mariner to cross species barriers, as well as to develop molecular genetic tools for studying zebrafish deve...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1985

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.82.6.1756